I talked about this before in Google+ but the paper +Alexander Anderson and myself authored at the Royal Society Interface focus is now available for everybody to see. This is a somewhat unconventional type of paper as it is not exactly a research paper, a review paper or an opinion piece but a combination of all those. I must apologise that the article is not in an open access journal but the version in arXiv has all the content (even if it’s not as pretty as the journal version). Also, at least for some time, the article can be downloaded from Interface Focus [PDF].
By the way, the visuals of the article, including the following sketch by +Arturo Araujo describing the ecosystem of prostate cancer metastasis to bone, are quite impressive I think.