Publications

  1. Frankenstein Z, Basanta D, Franco OE,  Gao Y, Javier RA, Strand DW, Lee MJ, Hayward SW, Ayala G, Anderson RA. Stromal reactivity deferentially drives tumor cell evolution and prostate cancer progression [bioRxiv][blog]
  2. Kaznatcheev A, Peacock J, Basanta D, Marusyk A, Scott JG.  Cancer associated fibroblasts  and alectinib switch the evolutionary games that non-small cell lung cancer plays. [bioRxiv]
  3. Gerlee P, Basanta D, Anderson ARA. The influence of cellular characteristics  on the evolution of shape homeostasis. Artif Life 2017 23(3):424-448 [link][arXiv]
  4. Salimi Sartakhti J, Manshaei MH, Basanta D, Sadegui M. Evolutionary emergence of angiogenesis in avascular tumors using a spatial public good games. PLOS One 2017 11;12(4):e0175063 [link]
  5. Basanta D, Anderson AR. Homeostasis back and forth: an ecoevolutionary  perspective of cancer. Cold Spring Harb Perspect Med a028332 [link][bioRxiv].
  6. Kaznatcheev A,  Vander Velde R, Scott JG, Basanta D. Cancer treatment scheduling  and dynamic heterogeneity in social dilemmas of tumor acidity and vascularity. Br J Cancer 2017 14;116(6):785-792 [link]
  7. Cook LM, Araujo A, Pow-Sang JM, Budzevich MM, Basanta D, Lynch CC.  Predictive Computational Modeling to define effective treatment strategies  for bone metastatic prostate cancer. Sci Rep. 2016 14;6;29384 [link]
  8. Kaznatcheev A, Scott JG, Basanta D. Edge effects in game-theoretic dynamics of spatially structured tumours. J R Soc Interface. 2015 Jul 6;12(108). pii: 20150154. doi: 10.1098/rsif.2015.0154. PMID 26040596. [link][bioRxiv][blog]
  9. Hummert S, Bohl K, Basanta D, Deutsch A, Werner S, Theissen G, Schroeter A, Schuster S. Evolutionary game theory: cells as players. Mol Biosyst. 2014 Dec;10(12):3044-65. doi: 10.1039/c3mb70602h. PMID: 25270362
  10. Frieling JS, Basanta D, Lynch CC. Current and emerging therapies for bone metastatic castration-resistant prostate cancer. Cancer Control. 2015 Jan;22(1):109-20. PMID: 25504285
  11. Bohl K1, Hummert S, Werner S, Basanta D, Deutsch A, Schuster S, Theißen G, Schroeter A. Evolutionary game theory: molecules as players Mol Biosyst. 2014 Oct 28;10(12):3066-74
  12. Baldock AL, Yagle K, Born DE, Ahn S, Trister AD, Neal M, Johnston SK, Bridge CA, Basanta D, Scott J, Malone H, Sonabend AM, Canoll P, Mrugala MM, Rockhill JK, Rockne RC, Swanson KR.Invasion and proliferation kinetics in enhancing gliomas predict IDH1 mutation status. Neuro Oncol. 2014 Jun;16(6):779-86
  13. Gallaher, J., Cook, L., Gupta, S., Araujo, A., Dhillon, J., Park, J., Scott, J., Pow-Sang, J.M., Basanta, D., Lynch, C.: Improving Treatment Strategies for Patients with Metastatic Castrate Resistant Prostate Cancer Through Personalized Computational Modeling. Clin Exp Metastasis, August 2014 [link][blog]
  14. Araujo, A, Cook, L, Lynch, C, Basanta D. An Integrated Computational Model of the Bone Microenvironment in Bone-Metastatic Prostate Cancer. Cancer Research May 1 2014 74;2391 [link][blog]
  15. Scott J, Hjelmeland A, Chinnaiyan P, Anderson ARA, Basanta D. Microenvironmental variables must influence intrinsic phenotypic parameters of cancer stem cells to affect tumourigenenicity. PLOS Computational Biology 2014 10(1) e1003433
  16. Kim E, Rebecca VW, Fedorenko IV, Messina JL, Mathew R, Maria-Engler SS, Basanta D, Smalley KS, Anderson AR. Senescent fibroblasts in melanoma initiation and progression: an integrated theoretical, experimental, and clinical approach. Cancer Research Dec 1 2013 73;6874
  17. Basanta D, Anderson ARA (2013). Exploiting ecological principles to better understand cancer progression and treatment. Interface Focus 6 v3 4 2013 [link][blog]
  18. Scott J, Basanta D, Anderson ARA, Gerlee P (2013). A mathematical model of tumour selfseeding reveals secondary metastatic deposits as drivers of primary tumour growth. J. R. Soc. 6 v10 82.
  19. Basanta D, Scott J. G., Fishman M N, Ayala G, Hayward S, Anderson ARA (2012). Investigating prostate cancer tumour–stroma interactions: clinical and biological insights from an evolutionary game. British Journal of Cancer. 106, 174-81
  20. Basanta D, Gatenby RA, Anderson AR. (2012) Exploiting evolution to treat drug resistance: combination therapy and the double bind. Mol Pharm. 2012 Apr 2;9(4):914-21 PMCID: PMC3325107
  21. Scott J. G., Basanta D, Chinnaiyan P, Canoll P, Swanson KR, Anderson ARA. (2011). Production of 2-hydroxyglutarate by isocitrate dehydrogenase 1-mutated gliomas: an evolutionary alternative to the Warburg shift? Neuro Oncol. 13 (12) 1262-64
  22. Gerlee P, Basanta D, Anderson AR. Evolving homeostatic tissue using genetic algorithms Prog Biophys Mol Biol. (2011) Aug;106(2):414-25. PMID:  21419156
  23. Basanta, D., Scott, J., Rockne, R., Swanson, K., Anderson, A. (2011) The role of IDH1 mutated tumour cells in secondary glioblastomas: an evolutionary game theoretical view. Physical Biology
  24. Hatzikirou, H., Basanta, D., Simon, M., Schaller, K., Deutsch, A. (2010). ‘Go or Grow’: the key to the emergence of invasion in tumour progression? Math Med Biol (2010)  PMID:  20610469
  25. Basanta, D., Ribba, B., Watkin, E., You, B., Deutsch, A. (2010) Computational analysis of the influence of microenvironment on carcinogenesis 2011 Jan;229(1):22-9. Epub 2010 Oct 31. PMID:  21044636
  26. Anderson AR, Hassanein M, Branch KM, Lu J, Lobdell NA, Maier J, Basanta D, Weidow B, Narasanna A, Arteaga CL, Reynolds AB, Quaranta V, Estrada L, Weaver AM. Microenvironmental independence associated with tumor progression Cancer Res. 2009 Nov 15;69(22):8797-806 PMCID: PMC2783510
  27. Basanta, D., Strand, D., Lukner, R., Franco, O., Ayala, G., Cliffel, D., Hayward, S., Anderson, A. (2009). The role of TGF-β mediated tumor-stroma interactions in prostate cancer progression: an integrative approach. Cancer Research, Cancer Res. 2009 Sep 1;69 (17):7111-20. Epub 2009 Aug 25.  PMCID:  PMC2748342
  28. Strand, D., Franco, O., Basanta, D., Anderson, A., Hayward, S. (2009). Perspectives on Tissue Interactions in Development and Disease. Curr. Mol. Med 10 (1):95-112.   PMID:  20205682
  29. Basanta, D., Simon, M. Hatzkikirou, H. and Deutsch, A. (2008). Evolutionary game theory elucidates the role of glycolysis in glioma progression and invasion.  Cell Proliferation 41 (6) 980, PMID:  19040573
  30. Basanta D, Miodownik M, Baum B. The Evolution of Robust Development and Homeostasis in Artificial Organism. PLoS Comput Biol 4(3)    PMCID:  PMC2274883
  31. D. Basanta, H. Hatzikirou and A. Deutsch. Studying the emergence of invasiveness in tumours using game theory European Physical Journal B 63 (3) 393-397 (2008)